IFITM1 CLIA Kit for Human(Homo sapiens) | EIAab.comIFITM1 CLIA Kit for Human(Homo sapiens)

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IFITM1 (Gene name),

Interferon-induced transmembrane protein 1 (Protein name ), IFM1_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

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Gene name:

IFITM1(CD225;IFI17);

Protein name:

Interferon-induced transmembrane protein 1;

Alternative:

Interferon-inducible protein 9-27;Interferon-induced protein 17(DSPA2a);Leu-13 antigen;Leu-13 antigen;

CD:

CD225;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Interacts with CAV1; this interaction enhances the ability of CAV1 in inhibiting ERK activation.

Function:

IFN-induced antiviral protein that mediate cellular innate immunity to at least three major human pathogens, namely influenza A H1N1 virus, West Nile virus, and dengue virus by inhibiting the early step(s) of replication. Plays a key role in the antiproliferative action of IFN-gamma either by inhibiting the ERK activition or by arresting cell growth in G1 phase in a p53-dependent manner. Implicated in the control of cell growth. Component of a multimeric complex involved in the transduction of antiproliferative and homotypic adhesion signals.

Subcellular Location:

Cell membrane Multi-pass membrane protein

Protein Attributes:

Sequence length:

125

Sequence:

50:

100:

125:

ILLLVFGSVT | VYHIMLQIIQ | EKRGY

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

UniGene:

Hs.458414

String:

P13164

Pfam:

PF04505

STRING:

9606.ENSP00000386187

KEGG:

hsa:8519

MIM:

604456

Uniprot:

P13164

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ELISA Kit for Human Interferon-induced transmembrane protein 1

Cat.:

E15511h

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Packing:

96T

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ELISA Kit for Human Interferon-induced transmembrane protein 1

Cat.:

E15511m

Price:

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Manual:

Looking for manual.

MSDS:

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Packing:

96T

Range:

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CLIA Kit for Human Interferon-induced transmembrane protein 1

Cat.:

U15511m

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MSDS:

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Packing:

96T

CLIA Kit for Human Interferon-induced transmembrane protein 1

Cat.:

U15511h

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MSDS:

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Packing:

96T

Polyclonal Antibody for Human Interferon-induced transmembrane protein 1

Cat.:

P15511Rb-m

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human Interferon-induced transmembrane protein 1

Cat.:

P15511Rb-h

Price:

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Packing:

40ug/0.2ml

Monoclonal Antibody for Human Interferon-induced transmembrane protein 1

Protein for Human Interferon-induced transmembrane protein 1

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

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Linearity

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References

1.

"A single DNA response element can confer inducibility by both alpha- and gamma-interferons."
Reid L.E. , Brasnett A.H. , Gilbert C.S. , Porter A.C.G. , Gewert D.R. , Stark G.R. , Kerr I.M.
Proc. Natl. Acad. Sci. U.S.A.86:840-844(1989) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];VARIANT ALA-13
2.

"Expression cloning of an interferon-inducible 17-kDa membrane protein implicated in the control of cell growth."
Deblandre G.A. , Marinx O.P. , Evans S.S. , Majjaj S. , Leo O. , Caput D. , Huez G.A. , Wathelet M.G.
J. Biol. Chem.270:23860-23866(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];VARIANT ALA-13
3.

"Cloning of human full-length CDSs in BD Creator(TM) system donor vector."
Kalnine N. , Chen X. , Rolfs A. , Halleck A. , Hines L. , Eisenstein S. , Koundinya M. , Raphael J. , Moreira D. , Kelley T. , LaBaer J. , Lin Y. , Phelan M. , Farmer A.
Submitted (2003-05) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA];VARIANT ALA-13
4.

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA];VARIANT ALA-13
tissue: Brain.
5.

"Human chromosome 11 DNA sequence and analysis including novel gene identification."
Taylor T.D. , Noguchi H. , Totoki Y. , Toyoda A. , Kuroki Y. , Dewar K. , Lloyd C. , Itoh T. , Takeda T. , Kim D.-W. , She X. , Barlow K.F. , Bloom T. , Bruford E. , Chang J.L. , Cuomo C.A. , Eichler E. , FitzGerald M.G. , more...
Nature440:497-500(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
6.

Mural R.J. , Istrail S. , Sutton G. , Florea L. , Halpern A.L. , Mobarry C.M. , Lippert R. , Walenz B. , Shatkay H. , Dew I. , Miller J.R. , Flanigan M.J. , Edwards N.J. , Bolanos R. , Fasulo D. , Halldorsson B.V. , Hannenhalli S. , Turner R. , more...
Submitted (2005-07) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA];VARIANT ALA-13
7.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA];VARIANT ALA-13
tissue: Cervix.
8.

"TAPA-1, the target of an antiproliferative antibody, is associated on the cell surface with the Leu-13 antigen."
Takahashi S. , Doss C. , Levy S. , Levy R.
J. Immunol.145:2207-2213(1990) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH CD81
9.

"IFITM1 plays an essential role in the antiproliferative action of interferon-gamma."
Yang G. , Xu Y. , Chen X. , Hu G.
Oncogene26:594-603(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
10.

"Binding of IFITM1 enhances the inhibiting effect of caveolin-1 on ERK activation."
Xu Y. , Yang G. , Hu G.
Acta Biochim. Biophys. Sin.41:488-494(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION;INTERACTION WITH CAV1
11.

"The IFITM proteins mediate cellular resistance to influenza A H1N1 virus, West Nile virus, and dengue virus."
Brass A.L. , Huang I.C. , Benita Y. , John S.P. , Krishnan M.N. , Feeley E.M. , Ryan B.J. , Weyer J.L. , van der Weyden L. , Fikrig E. , Adams D.J. , Xavier R.J. , Farzan M. , Elledge S.J.
Cell139:1243-1254(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN VIRAL RESISTANCE
12.

"The small interferon-induced transmembrane genes and proteins."
Siegrist F. , Ebeling M. , Certa U.
J. Interferon Cytokine Res.31:183-197(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REVIEW
13.

"Knockdown of interferon-induced transmembrane protein 1 (IFITM1) inhibits proliferation, migration, and invasion of glioma cells."
Yu F. , Ng S.S. , Chow B.K. , Sze J. , Lu G. , Poon W.S. , Kung H.F. , Lin M.C.
J. Neurooncol.103:187-195(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;TISSUE SPECIFICITY
14.

"The IFITM proteins inhibit HIV-1 infection."
Lu J. , Pan Q. , Rong L. , He W. , Liu S.L. , Liang C.
J. Virol.85:2126-2137(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
15.

Lu J. , Pan Q. , Rong L. , He W. , Liu S.L. , Liang C.
J. Virol.85:4043-4043(2011)

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ERRATUM
16.

"ISG56 and IFITM1 proteins inhibit hepatitis C virus replication."
Raychoudhuri A. , Shrivastava S. , Steele R. , Kim H. , Ray R. , Ray R.B.
J. Virol.85:12881-12889(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
17.

"Distinct patterns of IFITM-mediated restriction of filoviruses, SARS coronavirus, and influenza A virus."
Huang I.C. , Bailey C.C. , Weyer J.L. , Radoshitzky S.R. , Becker M.M. , Chiang J.J. , Brass A.L. , Ahmed A.A. , Chi X. , Dong L. , Longobardi L.E. , Boltz D. , Kuhn J.H. , Elledge S.J. , Bavari S. , Denison M.R. , Choe H. , Farzan M.
PLoS Pathog.7:E1001258-E1001258(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
18.

"IFITM1 increases osteogenesis through Runx2 in human alveolar-derived bone marrow stromal cells."
Kim B.S. , Kim H.J. , Kim J.S. , You Y.O. , Zadeh H. , Shin H.I. , Lee S.J. , Park Y.J. , Takata T. , Pi S.H. , Lee J. , You H.K.
Bone51:506-514(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;TISSUE SPECIFICITY
19.

"IFITM proteins restrict antibody-dependent enhancement of dengue virus infection."
Chan Y.K. , Huang I.C. , Farzan M.
PLoS ONE7:E34508-E34508(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
20.

"The dispanins: a novel gene family of ancient origin that contains 14 human members."
Sallman Almen M. , Bringeland N. , Fredriksson R. , Schioth H.B.
PLoS ONE7:E31961-E31961(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GENE FAMILY
21.

"A membrane topology model for human interferon inducible transmembrane protein 1."
Weston S. , Czieso S. , White I.J. , Smith S.E. , Kellam P. , Marsh M.
PLoS ONE9:E104341-E104341(2014) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION;TOPOLOGY
22.

"Initial characterization of the human central proteome."
Burkard T.R. , Planyavsky M. , Kaupe I. , Breitwieser F.P. , Buerckstuemmer T. , Bennett K.L. , Superti-Furga G. , Colinge J.
BMC Syst. Biol.5:17-17(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT [LARGE SCALE ANALYSIS] ALA-13;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]

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